The Constant Gardener
Directed by Fernando Meirelles
Star
rating:
****: Don't
miss
*: Don't
bother
Despite
its lacklustre title, this John le Carré adaptation is a
beautifully shot exploration of the workings of big pharmaceutical
companies. This is a multilayered film, part romance, part conspiracy
theory, and part espionage from the director of City of God. It
draws the audience in and leaves them in thoughtful appreciative
silence when it
ends.
The story is built around the relationship of Justin
Quayle (Ralph Fiennes) and his wife Tessa (Rachel Weisz). The first
scene is of the couple parting in Kenya, and this is followed soon
after by a gruesome scene in which Quayle must identify his dead
wife's charred body. Fiennes' mild mannered diplomat is
complemented by Weisz's portrayal of Tessa as a fiery political
activist whose passion leads her after Quayle to Nairobi. After her
death, it becomes apparent that although he loved his wife, he never
really knew her, and, paradoxically, he only comes closer to doing so
after her death.
The cinematography
is beautiful, with chaotic colourful scenes matched with tranquil
African landscapes. The film carries a strong anticorporate
antiestablishment message and, without preaching, it sends out its
message clearly. All this is set against a touching tragic love story.
Tessa and her fellow aid worker Arnold (Hubert Koundé) are
murdered and Quayle's employers at the British High Commission
are keen to paint it as a crime of
passion.
Quayle is broken by the
loss of his wife and channels his despair into discovering why his wife
was murdered and by whom. For the first time, he takes time away from
his own passion, gardening (hence the film's title) to pursue
what drew Tessa to Nairobi. It becomes apparent that she was never
fully honest with him as to what her activities were, as she felt that
she could protect him by keeping him in the dark. He starts unravelling
her work and begins to realise that she was almost single handedly
investigating the unethical practices of pharmaceutical companies in
Africa and that anyone who had come close to unearthing their
activities was threatened or
murdered.
He learns of the duplicity
with which drug companies operate and the intricacy of their
deceptions. He discovers that Dypraxa (an antituberculosis drug) is
being tested on unsuspecting African guinea pigs who are coerced into a
primitive form of informed consent with the threat that
their health care would be revoked if they do not comply. KVH, a
powerful multinational drug company, has bought Dypraxa and sold the
rights to distribute it in Africa to ThreeBees, another large company
based in Kenya. For the supposed two to three years that it may take
for tuberculosis to become a health problem in the West, ThreeBees is
to carry out its trials in Africa. KVH supposes that, by then, it can
buy ThreeBees out cheaply with the prospect of untold profits for
itself. The trial results are falsified, with any data indicating
serious side effects or even death conveniently
lost.
Taken as it is, this film is a
gently paced excerpt into one couple's life and the larger issues
surrounding the trialling of drugs in the developing world,
particularly Africa. It tragically emphasises the different worth
placed on the lives of people in different countries. You could not
imagine drug trials such as these ones done in the developing world
being carried out on such a scale in the developed world. It leads us
to wonder as to the number of people who have little choice or autonomy
at the hands of pharmaceutical companies, which act without compassion
or humanity.
The developing world is
an attractive place for pharmaceutical companies to trial drugs because
the cost for large studies is less prohibitive, and there are fewer
governmental restrictions and laws on research. Money can be used to
buy silence in the government and as gifts for children, which can be
given to participants who may not realise the extent to which they are
being used. On the flip side, perhaps the drugs we used could never
have completed their phase III if they were trialled in the developed
world at the magnified costs that would
entail.
Fiennes
gives a moving performance as the grief stricken husband; his
performance changes gear when he decides to pursue the truth and, at
that point, his British stiffness gives way to a sleuth character who
must hoodwink officials with false passports and lie his way to the
truth. Before losing his wife, he was a constant gardener, tending to
his foliage in London or Kenya. After her death, he digs behind the
lies of the officials he worked for and the corporate malfeasance to
get to the reality of what is
happening.
The film is at times
thriller and at times documentary, which makes it a moving depiction of
the exploitation and poverty occurring in Kenya. There is beauty in the
outdoor concert performed with bright colours and singing children in
Kenya and in its sandy landscapes. The camera work captures the
disparity of wealth as it swings from a tranquil manicured golf course
to the slums of a shanty town where barefoot children
play.
This fictional story draws on
the reality of what some may deem normal practice for the
pharmaceutical industry. The Constant Gardener is both visually
and intellectually stimulating, leading us to question where and on
whom the medicines that we give our patients each day have been
trialled and at what human cost.
I
am curious as to how much this story resembles reality or whether Le
Carré has used artistic license to portray his view of the
unethical code by which he supposes the pharmaceutical industry
functions.
Aula Abbara, F1
house officer, Central Middlesex
Hospital, London
Email: aula.abbara@imperial.ac.uk
studentBMJ 2006;14:1-44 January ISSN 0966-6494